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RORγt inverse agonist 14 [CAS 2672496-70-5]
RORγt inverse agonist 14 [CAS 2672496-70-5]
SKU:QM-0061921
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Product Details
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Description
RORγt inverse agonist 14 (8e) is a potent, orally active and selective RORγt inverse agonist (EC50 of 2.5 nM) with anti-inflammatory activity. RORγt inverse agonist 14 is used in the study for rheumatoid arthritis and psoriasis[1].
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CAS Number
[2672496-70-5]
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Molecular Formula
C26H26F8N2O6S2
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Molecular Weight
678.61
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Smiles
O=C(N[C@@H]1CC[C@@]2(S(=O)(C3=CC=C(F)C=C3)=O)C4=C(N=C(C(C(F)(F)F)(F)C(F)(F)F)C=C4)CC[C@]21[H])[C@](C)(O)CS(=O)(C)=O
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Target
ROR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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RORγt inverse agonist 14 [CAS 2672496-70-5]
RORγt inverse agonist 14 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.