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RORγt inverse agonist 31
RORγt inverse agonist 31
SKU:QM-0071895
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Product Details
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Description
RORγt inverse agonist 31 (14g) is a potent retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist, with an IC50 of 0.428 μM. RORγt inverse agonist 31 can alleviate the severity of Imiquimod -induced psoriasis in mice[1].
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Molecular Formula
C23H15Cl2F3N4O3S
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Molecular Weight
555.36
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Smiles
FC(C1=CC=C(C2=NC(NC3=CC=C(S(=O)(C)=O)C=C3)=NC(OC4=C(Cl)C=CC=C4Cl)=N2)C=C1)(F)F
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Target
ROR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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RORγt inverse agonist 31
RORγt inverse agonist 31 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.