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RORγt inverse agonist 35
RORγt inverse agonist 35
SKU:QM-0013771
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Product Details
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Description
RORγt inverse agonist 35 (Compound 22) is a RORγt inverse agonist with an IC50 of 1.51 μM. RORγt inverse agonist 35 significantly inhibits Th17 differentiation and proinflammatory properties in human CD4+ T cells. RORγt inverse agonist 35 can be used for research of Th17-driven autoimmune diseases, such as psoriasis, multiple sclerosis, and inflammatory bowel disease (IBD) [1].
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Molecular Formula
C25H23FN2O3S
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Molecular Weight
450.53
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Smiles
CC(S(=O)(C1=CC=C(C=C1)C2=CN3C=C(C=C3C=C2)C(NCC4=CC=C(C=C4)F)=O)=O)C
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Target
Interleukin Related; ROR
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Isoform
IL-17; IL-22; RORγ
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Shipping Conditions
Room temperature
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RORγt inverse agonist 35
RORγt inverse agonist 35 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.