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Rosiglitazone (sodium) [CAS 316371-83-2]
Rosiglitazone (sodium) [CAS 316371-83-2]
SKU:QM-0129370
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Product Details
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Description
Rosiglitazone sodium is a potent and selective activator of PPARγ, with EC50s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively, and a Kd of appr 40 nM for PPARγ; Rosiglitazone sodium is also an modulator of TRP channels, inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5) .
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CAS Number
[316371-83-2]
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Molecular Formula
C18H18N3NaO3S
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Molecular Weight
379.41
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Smiles
O=C([N-]1)SC(CC2=CC=C(OCCN(C)C3=NC=CC=C3)C=C2)C1=O.[Na+]
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Target
Autophagy; PPAR; TRP Channel
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Isoform
PPARγ
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Rosiglitazone (sodium) [CAS 316371-83-2]
Rosiglitazone (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.