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SEC inhibitor KL-2 [CAS 900308-51-2]

SEC inhibitor KL-2 [CAS 900308-51-2]

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QM-0076103-01

£103.75 GBP
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Product Details

  • Description

    SEC inhibitor KL-2 (KL-2), a peptidomimetic lead compound, is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. SEC inhibitor KL-2 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with a Ki of 1.50 μM[1].

  • CAS Number

    [900308-51-2]

  • Molecular Formula

    C17H13ClFNO3

  • Molecular Weight

    333.74

  • Smiles

    O=C(NC1=CC(Cl)=CC=C1C)/C(O)=C/C(C2=CC=C(F)C=C2)=O

  • Target

    DNA/RNA Synthesis

  • Concentration

    10mM

  • Purity

    99.49

  • Solubility

    DMSO : 83.33 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
1 mgQM-0076103-01
1 mgQM-0076103-01
£103.75/ea		 £0.00
£103.75/ea £0.00
5 mgQM-0076103-02
5 mgQM-0076103-02
£124.00/ea		 £0.00
£124.00/ea £0.00
10 mgQM-0076103-03
10 mgQM-0076103-03
£220.10/ea		 £0.00
£220.10/ea £0.00
25 mgQM-0076103-04
25 mgQM-0076103-04
£407.21/ea		 £0.00
£407.21/ea £0.00
50 mgQM-0076103-05
50 mgQM-0076103-05
£622.26/ea		 £0.00
£622.26/ea £0.00
100 mgQM-0076103-06
100 mgQM-0076103-06
£966.11/ea		 £0.00
£966.11/ea £0.00
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SEC inhibitor KL-2 [CAS 900308-51-2]

SEC inhibitor KL-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.