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SGC agonist 2 [CAS 2735713-77-4]
SGC agonist 2 [CAS 2735713-77-4]
SKU:QM-0065046
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Product Details
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Description
SGC agonist 2 is a potent agonist of soluble guanylate cyclase (SGC) . Soluble guanylate cyclase is a key signal transduction enzyme in the NO-sGC-cGMP signaling pathway. SGC agonist 2 has the potential for the research of cardiovascular disease (heart failure, pulmonary hypertension, angina, myocardial infarction) and fibrotic diseases (renal fibrosis, systemic sclerosis) (extracted from patent WO2021219088A1, compound 031) [1].
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CAS Number
[2735713-77-4]
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Molecular Formula
C23H17F2N7O2
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Molecular Weight
461.42
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Smiles
O=C1[C@]2([H])C3=C(N1)NC(C(C4=C5)=NN(CC6=C(C=CC=C6)F)C4=NC=C5F)=NC3=NC(C2(C)C)=O
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Target
Guanylate Cyclase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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SGC agonist 2 [CAS 2735713-77-4]
SGC agonist 2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.