SIRT6 activator 12q [CAS 2601734-99-8]
SIRT6 activator 12q [CAS 2601734-99-8]
SKU:QM-0149830-01
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Product Details
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Description
SIRT6 activator 12q is potent, selective and orally active SIRT6 activator with IC50 values of 171.20, >200, >200, >200, 0.58 μM for SIRT1, SIRT2, SIRT3, SIRT5, SIRT6, respectively. SIRT6 activator 12q inhibits cell growth and migration. SIRT6 activator 12q induces Apoptosis and cell cycle arrest at G2 phase. SIRT6 activator 12q shows anticancer activity[1].
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CAS Number
[2601734-99-8]
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Molecular Formula
C31H22N2O2
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Molecular Weight
454.52
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Smiles
O=C(C1=CC(C2=CC3=C(C=CC=C3)O2)=NC4=C1C=CC=C4)NC(C5=CC=CC=C5)C6=CC=CC=C6
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Target
Apoptosis; Sirtuin
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Isoform
SIRT6
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Purity
99.83
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Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 70°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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SIRT6 activator 12q [CAS 2601734-99-8]
SIRT6 activator 12q is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.