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SIRT7 inhibitor 97491 [CAS 1807758-81-1]

SIRT7 inhibitor 97491 [CAS 1807758-81-1]

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SKU:QM-0145272-01

£426.65 GBP
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  • Description

    SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.[1].

  • CAS Number

    [1807758-81-1]

  • Molecular Formula

    C15H12ClN3O

  • Molecular Weight

    285.73

  • Smiles

    NC1=CC(NC2=NC=C(C3=CC=C(Cl)C=C3)O2)=CC=C1

  • Target

    Apoptosis; Sirtuin

  • Isoform

    SIRT7

  • Purity

    98.81

  • Solubility

    DMSO : 500 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, protect from light)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H315, H319

  • Precautions

    H315, H319

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Variant Variant total Quantity Price Variant total
5 mgQM-0145272-01
5 mgQM-0145272-01
£426.65/ea
£0.00
£426.65/ea £0.00
10 mM - 1 mLQM-0145272-02
10 mM - 1 mLQM-0145272-02
£464.31/ea
£0.00
£464.31/ea £0.00
10 mgQM-0145272-03
10 mgQM-0145272-03
£614.98/ea
£0.00
£614.98/ea £0.00
25 mgQM-0145272-04
25 mgQM-0145272-04
£1,179.95/ea
£0.00
£1,179.95/ea £0.00
50 mgQM-0145272-05
50 mgQM-0145272-05
£1,870.07/ea
£0.00
£1,870.07/ea £0.00
100 mgQM-0145272-06
100 mgQM-0145272-06
£2,786.18/ea
£0.00
£2,786.18/ea £0.00

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SIRT7 inhibitor 97491 [CAS 1807758-81-1]

SIRT7 inhibitor 97491 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.