SPLA2-IIA Inhibitor [CAS 236394-37-9]
SPLA2-IIA Inhibitor [CAS 236394-37-9]
SKU:QM-0134075
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Product Details
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Description
SPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK (cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2) ), that binds to hGIIA (human IIA phospholipase A2) and inhibits its hydrolytic ability. sPLA2 is a member of the esterase superfamily that catalyzes the hydrolysis of the ester bond at the sn-2 position of glycerophospholipids, releasing free fatty acids such as arachidonic acid and lysophospholipids[1].
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CAS Number
[236394-37-9]
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Molecular Formula
C41H50N8O6
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Molecular Weight
750.89
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Smiles
O=C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC(C)C)=O)CO)=O)CC2=CC3=C(C=CC=C3)C=C2)=O)CCCNC(N)=N)N[C@H]1CC4=CC5=C(C=CC=C5)C=C4
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Target
Phospholipase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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SPLA2-IIA Inhibitor [CAS 236394-37-9]
SPLA2-IIA Inhibitor is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.