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SPSB2-iNOS inhibitory cyclic peptide-1 (TFA)

SPSB2-iNOS inhibitory cyclic peptide-1 (TFA)

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SKU:QM-0168519

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  • Description

    SPSB2-iNOS inhibitory cyclic peptide-1 TFA is the TFA salt form of SPSB2-iNOS inhibitory cyclic peptide-1. SPSB2-iNOS inhibitory cyclic peptide-1 is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 4.4 nM. SPSB2-iNOS inhibitory cyclic peptide-1 is resistant to the proteases pepsin, trypsin and α-chymotrypsin. SPSB2-iNOS inhibitory cyclic peptide-1 is stable in human plasma and in oxidative environment[1].

  • Molecular Formula

    C35H56N12O14S2.xC2HF3O2

  • Smiles

    CC[C@@H]([C@@]1([H])C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H](C(N1)=O)CC(O)=O)=O)C(C)C)=O)NC(C)=O)C(N)=O)=O)CC(N)=O)=O)CC(N)=O)=O)CC(N)=O)=O)C.O=C(C(F)(F)F)O.[x]

  • Target

    NO Synthase

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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SPSB2-iNOS inhibitory cyclic peptide-1 (TFA)

SPSB2-iNOS inhibitory cyclic peptide-1 (TFA) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.