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STGFBR3 antagonist 1
STGFBR3 antagonist 1
SKU:QM-0088108
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Product Details
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Description
STGFBR3 antagonist 1 (Compound p24) is an antagonist for soluble transforming growth factor beta receptor 3 (sTGFBR3), thus activates TGF-β signaling pathway, and inhibits IκBα/NF-κB signaling pathway. sTGFBR3 antagonist 1 inhibits NO-release in LPS -induced BV2 cells with an IC50 of 0.52 μM. sTGFBR3 antagonist 1 exhibits anti-inflammatory and neuroprotective activities with blood brain barrier (BBB) permeability. sTGFBR3 antagonist 1 can be used in Alzheimer’s Disease research[1].
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Molecular Formula
C21H21NO5
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Molecular Weight
367.4
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Smiles
O=C1C2=C(C=C(OCC(NCC3CCOCC3)=O)C=C2)OC4=CC=CC=C41
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Target
TGF-β Receptor
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Shipping Conditions
Room temperature
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STGFBR3 antagonist 1
STGFBR3 antagonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.