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STING agonist-44
STING agonist-44
SKU:QM-0013755
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Product Details
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Description
STING agonist-44 (Compound 4) is a potent and selective STING agonist with an EC50 value of 5.68 for IRF induction in THP1 cells and 2.212 μM in RAW cells. STING agonist-44 activates the STING pathway, inducing the production of type I interferons and pro-inflammatory cytokines (e.g., CXCL10, TNFα) . STING agonist-44 is promising for research of cancers[1].
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Molecular Formula
C21H24N10O12P2S
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Molecular Weight
702.49
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Smiles
O[C@H]1[C@@H](OP(SC[C@]23[C@@H](O4)[C@@H](OC3)[C@H](N5C=NC6=C5N=CN=C6N)O2)(O)=O)[C@H](N(C=N7)C8=C7C(NC(N)=N8)=O)O[C@@H]1COP4(O)=O
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Target
STING
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Shipping Conditions
Room temperature
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STING agonist-44
STING agonist-44 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.