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STING agonist-48 [CAS 3027712-31-5]
STING agonist-48 [CAS 3027712-31-5]
SKU:QM-0015612
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Product Details
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Description
STING agonist-48 is a potent STING agonist that exhibits STING-dependent activity in vitro (EC50 = 4.02 μM) . STING agonist-48 prefers to bind with the transmembrane domain (TMD) over the cytosolic cyclic dinucleotide (CDN) domain. STING agonist-48 shows adjuvant efficacy, enhancing IgG and Th1/Th2 cytokine responses in humanized STING mice. STING agonist-48 can be used for the study of inflammation-related diseases[1].
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CAS Number
[3027712-31-5]
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Molecular Formula
C23H16F4N2O3S
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Molecular Weight
476.44
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Smiles
O=C(C1=CC=C(N2CC3=C(O)C=CC=C3F)C(SCC2=O)=C1)NCC4=C(F)C=C(F)C=C4F
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Target
STING
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Shipping Conditions
Room temperature
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STING agonist-48 [CAS 3027712-31-5]
STING agonist-48 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.