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Syk Inhibitor II (dihydrochloride) [CAS 227449-73-2]
Syk Inhibitor II (dihydrochloride) [CAS 227449-73-2]
SKU:QM-0058495
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Product Details
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Description
Syk Inhibitor II dihydrochloride is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II dihydrochloride inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II dihydrochloride shows less potent against other kinases and has anti-allergic effect[1].
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CAS Number
[227449-73-2]
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Molecular Formula
C14H17Cl2F3N6O
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Molecular Weight
413.23
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Smiles
O=C(C1=CN=C(NCCN)N=C1NC2=CC=CC(C(F)(F)F)=C2)N.[H]Cl.[H]Cl
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Target
5-HT Receptor; Syk
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Isoform
MUC4
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Syk Inhibitor II (dihydrochloride) [CAS 227449-73-2]
Syk Inhibitor II (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.