Syrosingopine [CAS 84-36-6]
Syrosingopine [CAS 84-36-6]
SKU:QM-0165566-01
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Product Details
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Description
Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, which can reduce glycolysis and induce synthetic lethality in cancer cells when combine with metformin. Syrosingopine shows anti-hypertensive activity by depleting peripheral stores of norepinephrine[1][2].
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CAS Number
[84-36-6]
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Molecular Formula
C35H42N2O11
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Molecular Weight
666.71
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Smiles
[H][C@@]12C(NC3=C4C=CC(OC)=C3)=C4CCN1C[C@]5(C[C@@H](OC(C6=CC(OC)=C(OC(OCC)=O)C(OC)=C6)=O)[C@H](OC)[C@@H](C(OC)=O)[C@]5(C2)[H])[H]
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Target
Monocarboxylate Transporter
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Isoform
MCT1; MCT4
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Concentration
10mM
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Purity
99.52
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Solubility
DMSO : 62.5 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Syrosingopine [CAS 84-36-6]
Syrosingopine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.