Tau ligand-1 [CAS 3063166-64-0]
Tau ligand-1 [CAS 3063166-64-0]
SKU:QM-0011391
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Product Details
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Description
Tau ligand-1 (Compound 75) is a ligand for aggregated tau protein that can penetrate the blood-brain barrier[1]. In tissues from patients with Alzheimer's disease, progressive supranuclear palsy, corticobasal degeneration, and Pick's disease, Tau ligand-1 exhibits high affinity for aggregated tau protein, with equilibrium dissociation constant (KD) values ranging from 1 to 3.8 nM[1]. Tau ligand-1 can serve as a potential positron emission tomography (PET) tracer and holds promise for application in positron emission tomography imaging studies of tau-related diseases in the central nervous system[1].
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CAS Number
[3063166-64-0]
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Molecular Formula
C17H16FN3O
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Molecular Weight
297.33
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Smiles
FC1=NC(N2CCOCC2)=CC=C1C3=CC4=C(N3)C=CC=C4
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Target
Tau Protein
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Shipping Conditions
Room temperature
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Tau ligand-1 [CAS 3063166-64-0]
Tau ligand-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.