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THR-β agonist 6 [CAS 2791290-58-7]
THR-β agonist 6 [CAS 2791290-58-7]
SKU:QM-0068197
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Product Details
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Description
THR-β agonist 6 is an orally active, selective thyroid hormone receptor β (THR-β) agonist with EC50s of 0.03 μM and 0.22 μM for THR-β and THR-α, respectively. THR-β agonist 6 exhibits an xcellent liver-to-serum ratio of 93:1 in mice. THR-β agonist 6 has the potential for nonalcoholic steatohepatitis (NASH) research[1].
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CAS Number
[2791290-58-7]
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Molecular Formula
C20H14Cl2N6O3
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Molecular Weight
457.27
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Smiles
CC(C)N1C(C=CC2=C1C=CN2C3=C(Cl)C=C(N4N=C(C#N)C(NC4=O)=O)C=C3Cl)=O
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Target
Thyroid Hormone Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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THR-β agonist 6 [CAS 2791290-58-7]
THR-β agonist 6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.