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TLR2 antagonist-1
TLR2 antagonist-1
SKU:QM-0013238
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Product Details
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Description
TLR2 antagonist-1 is a selective Toll-like receptor 2 (TLR2) antagonist. TLR2 antagonist-1 can effectively inhibit excessive TLR2 activation (IC50 = 11.41 μM) and the production of inflammatory factors. TLR2 antagonist-1 has metabolic stability with a half-life (T1/2) of 16.67 min in mouse liver microsomes. TLR2 antagonist-1 can be used for the researches of inflammation, immunology, and neurological disease[1].
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Molecular Formula
C18H15ClFN3O4
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Molecular Weight
391.78
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Smiles
C/C(C1=CC=C(O)C(O)=C1Cl)=N\OCC2=CC(C3=NOC(C)=N3)=CC(F)=C2
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Target
Toll-like Receptor (TLR)
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Isoform
TLR2
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Shipping Conditions
Room temperature
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TLR2 antagonist-1
TLR2 antagonist-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.