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TLR7/8/9 antagonist 2 [CAS 2920729-91-3]
TLR7/8/9 antagonist 2 [CAS 2920729-91-3]
SKU:QM-0070618
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Product Details
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Description
TLR7/8/9 antagonist 2 is an orally active TLR7/8/9 antagonist. TLR7/8/9 antagonist 2 has inhibitory activities for HEK/hTLR7, HEK/hTLR8 and HEK/hTLR9 with IC50 values of 0.011 μM, 0.029 μM and 0,052 μM, respectively.TLR7/8/9 antagonist 2 has high bioavailability in vivo.TLR7/8/9 antagonist 2 can be used for the research of auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis[1].
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CAS Number
[2920729-91-3]
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Molecular Formula
C23H31N7
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Molecular Weight
405.54
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Smiles
CN1N=CC2=C(C=C(C)N=C21)N(CC3)CCC3C4=NC=C(N5CCNCC5)C=C4C
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Target
Toll-like Receptor (TLR)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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TLR7/8/9 antagonist 2 [CAS 2920729-91-3]
TLR7/8/9 antagonist 2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.