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TLR7/8 agonist 14
TLR7/8 agonist 14
SKU:QM-0015951
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Product Details
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Description
TLR7/8 agonist 14 is a TLR7 and TLR8 agonist with EC50 values of 0.53 μM and 4.3 μM, respectively. TLR7/8 agonist 14 increases the secretion of the proinflammatory cytokines TNF-α, IL-1β, IL-8 and IFN-γ. TLR7/8 agonist 14 increases cytokine secretion and expression of CD86. LR7/8 agonist 14 can be used for research colorectal carcinoma[1].
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Molecular Formula
C17H23ClN2O2
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Molecular Weight
322.83
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Smiles
O=C1N(C(CCCCCC)CO)C=NC2=C1C(C)=CC=C2Cl
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Target
IFNAR; Interleukin Related; TNF Receptor; Toll-like Receptor (TLR)
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Isoform
IL-1; IL-8; TLR7; TLR8; TNFRSF5/CD40
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Shipping Conditions
Room temperature
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TLR7/8 agonist 14
TLR7/8 agonist 14 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.