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TLR7/8 agonist 8 [CAS 2649170-16-9]
TLR7/8 agonist 8 [CAS 2649170-16-9]
SKU:QM-0070677-01
£753.49 GBP
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Product Details
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Description
TLR7/8 agonist 8 (compound 24m) is a potent toll-like receptor 7/8 (TLR7/8) dual agonist, with EC50s of 27 and 12 nM for hTLR7 and hTLR8, respectively. TLR7/8 agonist 8 can improve the antitumor activity of PD-1/PD-L1 blockade[1].
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CAS Number
[2649170-16-9]
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Molecular Formula
C24H30N6O
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Molecular Weight
418.53
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Smiles
CCCCNC1=C2N=C(CC3=CC=C(CN4CC5(C4)COC5)C=C3)C=CC2=NC(N)=N1
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Target
Toll-like Receptor (TLR)
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Isoform
TLR7; TLR8
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Purity
98.69
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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TLR7/8 agonist 8 [CAS 2649170-16-9]
TLR7/8 agonist 8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.