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TLR7/8 antagonist 1 [CAS 2901020-63-9]
TLR7/8 antagonist 1 [CAS 2901020-63-9]
SKU:QM-0066442
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Product Details
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Description
TLR7/8 Antagonist 1 (Compound 16c) is the potent antagonist of TLR7/8 with IC50s of 3.91 and 2.19 μM, respectively. TLR7/8 Antagonist 1 is an imidazoquinoline derivative compound. Toll-like receptors (TLRs) 7 and 8 are key targets in the development of immunomodulatory drugs for researching infectious disease, cancer, and autoimmune disorders[1].
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CAS Number
[2901020-63-9]
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Molecular Formula
C24H27N5O2
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Molecular Weight
417.5
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Smiles
COC(C1=CC2=NC(N)=C3N=C(N(C3=C2C=C1)CC4=CC=C(CN)C=C4)CC(C)C)=O
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Target
Toll-like Receptor (TLR)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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TLR7/8 antagonist 1 [CAS 2901020-63-9]
TLR7/8 antagonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.