TLR7 agonist 13 [CAS 2389988-70-7]
TLR7 agonist 13 [CAS 2389988-70-7]
SKU:QM-0071122
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Product Details
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Description
TLR7 agonist 13 is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) [1]. TLR7 agonist 13 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CAS Number
[2389988-70-7]
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Molecular Formula
C17H19N5O6
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Molecular Weight
389.36
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Smiles
O=C1N(CC#C)C2=C(N=C(N)N=C2)N1[C@@H]3O[C@H](COC(C)=O)C[C@H]3OC(C)=O
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Target
Nucleoside Antimetabolite/Analog
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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TLR7 agonist 13 [CAS 2389988-70-7]
TLR7 agonist 13 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.