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TLR7 agonist 18
TLR7 agonist 18
SKU:QM-0073486
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Product Details
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Description
TLR7 agonist 18 (Compound 21a) is a selective Toll-like receptor 7 (TLR7) agonist with an EC50 of 7.8 μM. TLR7 agonist 18 is not cytotoxic to hTLR7 cotransfected HEK293 cell lines and can induce the secretion of several cytokines, including IL-1β, IL-12p70, IL-8, and TNF-α. TLR7 agonist 18 can be used in vaccine, asthma, allergy and anti-cancer research[1].
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Molecular Formula
C18H16F4N4O
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Molecular Weight
380.34
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Smiles
FC(C1=NC(N2CC(C)CCC2)=C3C(ON=C3C4=CC=C(F)C=C4)=N1)(F)F
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Target
Toll-like Receptor (TLR)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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TLR7 agonist 18
TLR7 agonist 18 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.