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TLR7 agonist 21
TLR7 agonist 21
SKU:QM-0131781
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Product Details
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Description
TLR7 agonist 21 (Compound 27B) is a selective agonist for Toll-like receptor 7 (TLR7), with an EC50 of 17.53 nM (for human TLR7) and 41.7 nM (for mouse TLR7) . TLR7 agonist 21 stimulates the secretion of pro-inflammatory cytokines, such as IL-6, TNF-α, IFN-α1, and IL-4. TLR7 agonist 21 acts as a vaccine adjuvant, increases levels of IgG and IgA, and protects the mouse from influenza virus infections[1].
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Molecular Formula
C22H33N7O
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Molecular Weight
411.54
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Smiles
NC1=NC2=C(C(NCCCC)=N1)N(C=N2)CC3=CC=C(C=C3OC)CN(CC)CC
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Target
Toll-like Receptor (TLR)
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Isoform
TLR7; TLR8
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Shipping Conditions
Room temperature
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TLR7 agonist 21
TLR7 agonist 21 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.