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TLR7 agonist 22 [CAS 3036114-68-5]
TLR7 agonist 22 [CAS 3036114-68-5]
SKU:QM-0121155
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Product Details
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Description
TLR7 agonist 22 (Compound 11a) emerges as a selective TLR7 agonist with an IC50 value of 25.86 μM. TLR7 agonist 22 inhibits the cellular HBsAg secretion and effectively activates TLR7, thereby inducing the secretion of TLR7-regulated cytokines IL-12, TNF-αand IFN-αin human PBMC cells. TLR7 agonist 22 is a promising for research in the field of developing novel immunomodulatory anti-HBV agents[1].
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CAS Number
[3036114-68-5]
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Molecular Formula
C20H17FN2O2S
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Molecular Weight
368.42
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Smiles
FC1=C(OCC2=NC(CC(N3CCC4=C3C=CC=C4)=O)=CS2)C=CC=C1
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Target
Toll-like Receptor (TLR)
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Shipping Conditions
Room temperature
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TLR7 agonist 22 [CAS 3036114-68-5]
TLR7 agonist 22 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.