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Topoisomerase I/II inhibitor 2 [CAS 2770804-58-3]
Topoisomerase I/II inhibitor 2 [CAS 2770804-58-3]
SKU:QM-0065276
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Product Details
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Description
Topoisomerase I/II inhibitor 2 (compound 1a) is a potent Topoisomerase inhibitor (IC50= 9.82 μM on Huh7 cells and 6.83 μM on LM9 cells) . Topoisomerase I/II inhibitor 2 has dual inhibition on DNA topoisomerase I/II, also can obviously reduce the growth of xenograft tumor in mice model. Topoisomerase I/II inhibitor 2 has the potential value in researching liver cancer[1].
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CAS Number
[2770804-58-3]
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Molecular Formula
C19H16N2O4
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Molecular Weight
336.34
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Smiles
CNCC1=CC2=C(OCO2)C=C1C3=CC4=C(C5=C(OCO5)C=C4)C=N3
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Target
Topoisomerase
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Isoform
Topo I; Topo II
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Topoisomerase I/II inhibitor 2 [CAS 2770804-58-3]
Topoisomerase I/II inhibitor 2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.