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Topoisomerase I inhibitor 14

Topoisomerase I inhibitor 14

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SKU:QM-0109957

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  • Description

    Topoisomerase I inhibitor 14 (Compound 4h) is an inhibitor for Topoisomerase I. Topoisomerase I inhibitor 14 inhibits proliferation of A549 and C6 with IC50s of 4.56 μM and 13.17 μM, without significant toxicity in healthy cells NIH3T3 (IC50 is 74.44 μM), which exhibits anticancer potency[1].

  • Molecular Formula

    C28H29N9O2S

  • Molecular Weight

    555.65

  • Smiles

    COC1=CC=C(C2=NC3=CC=C(C4=NN=C(SCC(N5CCN(C6=NC=CC=N6)CC5)=O)N4CC)C=C3N2)C=C1

  • Target

    Topoisomerase

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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Topoisomerase I inhibitor 14

Topoisomerase I inhibitor 14 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.