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Topoisomerase I inhibitor 16
Topoisomerase I inhibitor 16
SKU:QM-0130108
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Product Details
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Description
Topoisomerase I inhibitor 21 (Compound 3e) is an inhibitor for Topoisomerase I through stabilization of enzyme-DNA complex. Topoisomerase I inhibitor 21 exhibits antiproliferative activity in 39 human cancer cells (JFCR39) with mean GI50 39 nM[1].
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Molecular Formula
C27H27N3O4
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Molecular Weight
457.52
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Smiles
OC1=CC2=C(C=C1)C3=C(C(N=CC4=C5C=C(OC)C(O)=C4)=C5N3CCCN6CCOCC6)C=C2
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Target
Topoisomerase
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Isoform
Topo I
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Topoisomerase I inhibitor 16
Topoisomerase I inhibitor 16 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.