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Topoisomerase I inhibitor 2 [CAS 2588211-44-1]
Topoisomerase I inhibitor 2 [CAS 2588211-44-1]
SKU:QM-0065199
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Product Details
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Description
Topoisomerase I inhibitor 2 (ZML-8) is a highly selective inhibitor of DNA topoisomerase I (Top1) . Topoisomerase I inhibitor 2 inhibits Top1 activity and results DNA damage. Topoisomerase I inhibitor 2 blocks G2/M phase and induces apoptosis, exhibits anti-tumor effect[1].
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CAS Number
[2588211-44-1]
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Molecular Formula
C18H15NO3
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Molecular Weight
293.32
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Smiles
COC1=C(C=C2N=C3COC4=C(C3=CC2=C1)C=CC=C4)OC
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Target
Apoptosis; Caspase; Topoisomerase
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Isoform
Topo I
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Topoisomerase I inhibitor 2 [CAS 2588211-44-1]
Topoisomerase I inhibitor 2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.