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Topoisomerase I inhibitor 5 [CAS 2513461-95-3]
Topoisomerase I inhibitor 5 [CAS 2513461-95-3]
SKU:QM-0066003
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Product Details
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Description
Topoisomerase I inhibitor 5 is an effective topoisomerase inhibitor with IC50 value of. Topoisomerase I inhibitor 5 can interfere with DNA and significantly inhibit the activity of Topoisomerase I. Topoisomerase I inhibitor 5 can arrest cell cycle at the G1 phase and induce MCF-7 cells apoptosis. Topoisomerase I inhibitor 5 has potency in reversing P-gp-mediated resistance to Adriamycin[1].
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CAS Number
[2513461-95-3]
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Molecular Formula
C24H24N2O2
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Molecular Weight
372.46
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Smiles
O=C(C1=CC=CC=C12)C3=CC=C(OCCN4C(C)CCCC4)C5=CC=NC2=C53
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Target
Apoptosis; DNA/RNA Synthesis; Topoisomerase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Topoisomerase I inhibitor 5 [CAS 2513461-95-3]
Topoisomerase I inhibitor 5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.