Topoisomerase II inhibitor 23
Topoisomerase II inhibitor 23
SKU:QM-0011990
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Product Details
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Description
Topoisomerase II inhibitor 23 is a potent topoisomerase II inhibitor (IC50 = 0.94 μM) . Topoisomerase II inhibitor 23 shows high selectivity and exceptional cytotoxic activity in MCF-7, HepG2, and HCT116 cells. Topoisomerase II inhibitor 23 induces cell cycle arrest at the G1 phase, leading to inhibition of cell proliferation. Topoisomerase II inhibitor 2 induces apoptosis by up-regulating the pro-apoptotic Bax level and down-regulating the anti-apoptotic Bcl-2 level[1].
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Molecular Formula
C28H23BrN2O2S
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Molecular Weight
531.46
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Smiles
CC1=CC=C(C2=CSC3=NC(C4=CC=CC=C4)=C(C(OCC)=O)C(C5=CC=C(Br)C=C5)N32)C=C1
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Target
Apoptosis; Bcl-2 Family; Topoisomerase
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Shipping Conditions
Room temperature
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Topoisomerase II inhibitor 23
Topoisomerase II inhibitor 23 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.