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Topoisomerase IV inhibitor 1 [CAS 2883403-42-5]
Topoisomerase IV inhibitor 1 [CAS 2883403-42-5]
SKU:QM-0059180
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Product Details
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Description
Topoisomerase IV inhibitor 2 (compound 7d) is a potent DNA topoisomerase IV (TOPO IV) inhibitor with IC50s of 0.23 μM and 0.43 μM for TOPO IV and DNA gyrase, respectively. Topoisomerase IV inhibitor 2 has anti-bacterial activity, with MICs of 0.972 μM and 0.608 μM in Staphylococcus aureus Newman and Escherichia coli ATCC8739, respectively[1].
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CAS Number
[2883403-42-5]
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Molecular Formula
C34H32FN7O6S
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Molecular Weight
685.72
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Smiles
O=C(NC1=CC=C(C=C1)S(=O)(NC2=NC3=C(N=C2)C=CC=C3)=O)CCN4CCN(CC4)C5=CC6=C(C(C(C(O)=O)=CN6C7CC7)=O)C=C5F
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Target
Bacterial; Topoisomerase
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Isoform
Topoisomerase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Topoisomerase IV inhibitor 1 [CAS 2883403-42-5]
Topoisomerase IV inhibitor 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.