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Tpl2 Kinase Inhibitor 1 (hydrochloride) [CAS 2934185-09-6]
Tpl2 Kinase Inhibitor 1 (hydrochloride) [CAS 2934185-09-6]
SKU:QM-0004957
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Product Details
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Description
Tpl2 Kinase Inhibitor 1 hydrochloride is a 3-pyridylmethylamino analog, and is a selective Tpl2 inhibitor (IC50=50 nM) . Tpl2 consists of COT kinase and MAP3K8. Tpl2 Kinase Inhibitor 1 hydrochloride plays an important role in the regulation of the inflammatory response and the progression of some cancers[1][2].
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CAS Number
[2934185-09-6]
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Molecular Formula
C21H15Cl2FN6
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Molecular Weight
441.29
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Smiles
FC1=CC=C(NC2=C(C=NC3=C2C=C(NCC4=CN=CC=C4)N=C3)C#N)C=C1Cl.Cl
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Target
MAP3K; MAPKAPK2 (MK2) ; p38 MAPK
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Isoform
MAP3K8/COT/Tpl2; p38 MAPK
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Shipping Conditions
Room temperature
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Tpl2 Kinase Inhibitor 1 (hydrochloride) [CAS 2934185-09-6]
Tpl2 Kinase Inhibitor 1 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.