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Tubulin inhibitor 42 [CAS 2135713-96-9]
Tubulin inhibitor 42 [CAS 2135713-96-9]
SKU:QM-0095012
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Product Details
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Description
Tubulin inhibitor 42 (Compound 14b) dose-dependently inhibited the activity of β-microtubulin (IC50 = 3.5 µM) .Tubulin inhibitor 42 interferes with microtubule dynamic homeostasis, resulting in the arrest of the cancer cell cycle in the G2/M phase and inducing apoptosis. Tubulin inhibitor 42 significantly inhibits the angiogenic process in vitro and in vivo, preventing vascularization and tumor growth[1].
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CAS Number
[2135713-96-9]
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Molecular Formula
C20H23NO7
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Molecular Weight
389.4
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Smiles
OC[C@H]1[C@H](C2=CC(O)=C(C=C2)OC)N(C3=CC(OC)=C(C(OC)=C3)OC)C1=O
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Target
Apoptosis; Microtubule/Tubulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Tubulin inhibitor 42 [CAS 2135713-96-9]
Tubulin inhibitor 42 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.