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Type II topoisomerase inhibitor 1 [CAS 2245691-60-3]
Type II topoisomerase inhibitor 1 [CAS 2245691-60-3]
SKU:QM-0068774
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Product Details
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Description
Type II topoisomerase inhibitor 1 is a potent and selective E. coli DNA gyrase inhibitor (IC50: 1.7 nM), and forms hydrogen bonds with Asp73 residue. Type II topoisomerase inhibitor 1 inhibits topoisomerase IV activity (IC50: 0.98 μM) . Type II topoisomerase inhibitor 1 can be used in the research of antibacterial area[1][2].
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CAS Number
[2245691-60-3]
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Molecular Formula
C18H15N3O4
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Molecular Weight
337.33
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Smiles
CNC1=CC=CC2=C1NC(C(C(NC3=CC=C(C=C3)C(O)=O)=O)=C2)=O
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Target
Bacterial; DNA/RNA Synthesis; Topoisomerase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Type II topoisomerase inhibitor 1 [CAS 2245691-60-3]
Type II topoisomerase inhibitor 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.