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WRN inhibitor 10
WRN inhibitor 10
SKU:QM-0108359
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Product Details
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Description
WRN inhibitor 10 (Compound P24) is an inhibitor for the Werner helicase WRN with an IC50 of 1.1 nM. WRN inhibitor 10 inhibits the proliferation of cancer cell SW48 with IC50 of 39 nM. WRN inhibitor 10 exhibits good liver microsomal stability and film permeability. WRN inhibitor 10 exhibits good pharmacokinetic characteristics in CD-1 mice[1].
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Molecular Formula
C31H29BrClN9O5S
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Molecular Weight
755.04
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Smiles
O=C(N1CCN(CC1)C2=C(N(C3=NC(C4=CC5=C(S4)COC5)=NN3C2=O)CC(NC6=CC=C(C=C6Cl)Br)=O)CC)C7=NC=NC(C)=C7O
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Target
DNA/RNA Synthesis
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Shipping Conditions
Room temperature
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WRN inhibitor 10
WRN inhibitor 10 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.