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ZBP1/RIP3/MLKL activator 1

ZBP1/RIP3/MLKL activator 1

Size

QM-0089589-01

£238.32 GBP
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Product Details

  • Description

    ZBP1/RIP3/MLKL activator 1 (compound 3a) is a synthetically derived quinoline compound. ZBP1/RIP3/MLKL Activator 1 induces DNA damage, enhances intracellular levels of reactive oxygen species (ROS), and triggers apoptosis via the caspase pathway. Furthermore, when apoptosis is inhibited, ZBP1/RIP3/MLKL Activator 1 promotes necroptotic cell death through the ZBP1-RIP3-MLKL pathway. ZBP1/RIP3/MLKL Activator 1 is utilized in oncological research, particularly in the selective targeting of cells with impaired apoptotic function[1].

  • Molecular Formula

    C26H28N6O2

  • Molecular Weight

    456.54

  • Smiles

    CN(C)CCCNC1=NC2=CC([N+]([O-])=O)=CC=C2N=C1NCC3=CC=C(C4=CC=CC=C4)C=C3

  • Target

    Mixed Lineage Kinase; Necroptosis; RIP kinase

  • Purity

    99.73

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, protect from light, stored under nitrogen)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0089589-01
5 mgQM-0089589-01
£238.32/ea		 £0.00
£238.32/ea £0.00
10 mM - 1 mLQM-0089589-02
10 mM - 1 mLQM-0089589-02
£239.54/ea		 £0.00
£239.54/ea £0.00
10 mgQM-0089589-03
10 mgQM-0089589-03
£363.47/ea		 £0.00
£363.47/ea £0.00
25 mgQM-0089589-04
25 mgQM-0089589-04
£715.82/ea		 £0.00
£715.82/ea £0.00
50 mgQM-0089589-05
50 mgQM-0089589-05
£1,116.77/ea		 £0.00
£1,116.77/ea £0.00
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ZBP1/RIP3/MLKL activator 1

ZBP1/RIP3/MLKL activator 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.