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CAIX/CDK-2-IN-1

CAIX/CDK-2-IN-1

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SKU:QM-0015666

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  • Description

    CAIX/CDK-2-IN-1 is a dual-acting inhibitor of carbonic anhydrase IX (CA IX) and cyclin-dependent kinase-2 (CDK-2) with IC50 values of 0.29 μM and 0.32 μM. The zein nanoparticls of CAIX/CDK-2-IN-1 can induce cancer cells apoptosis. CAIX/CDK-2-IN-1 can be used for the research of cancer, such as lung cancer[1].

  • Molecular Formula

    C25H18ClN5O4S3

  • Molecular Weight

    584.09

  • Smiles

    ClC1=CC=C(C2=NC(N=C(SCC(NC3=CC=C(S(=O)(N)=O)C=C3)=O)NC4=O)=C4C(C5=CC=CS5)=C2)C=C1

  • Target

    Apoptosis; Bcl-2 Family; Carbonic Anhydrase; Caspase; CDK; MDM-2/p53

  • Isoform

    Bax; Bcl-2; CA IX; Caspase 3; Caspase 8; Caspase 9; CDK2

  • Shipping Conditions

    Room temperature

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CAIX/CDK-2-IN-1

CAIX/CDK-2-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.