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CDK12/13-IN-2 [CAS 3076450-41-1]

CDK12/13-IN-2 [CAS 3076450-41-1]

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SKU:QM-0011162

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  • Description

    CDK12/13-IN-2 (Compound 24) is a covalent inhibitor of CDK12/13, with IC50 values of 15.5 nM and 12.2 nM for CDK12 and CDK13, respectively. CDK12/13-IN-2 can inhibit the proliferation of breast cancer cells and can be used in the research of triple-negative breast cancer[1].

  • CAS Number

    [3076450-41-1]

  • Molecular Formula

    C24H22FN7O2

  • Molecular Weight

    459.48

  • Smiles

    C=CC(NC1=CC=C(C2=NN3C(C=C2)=NC(CC(NC4=NNC(C5CCC5)=C4)=O)=C3)C=C1F)=O

  • Target

    CDK

  • Isoform

    CDK12; CDK13

  • Shipping Conditions

    Room temperature

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CDK12/13-IN-2 [CAS 3076450-41-1]

CDK12/13-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.