1
/
of
1
CDK2 degrader 1 [CAS 3036604-59-5]
CDK2 degrader 1 [CAS 3036604-59-5]
SKU:QM-0153621-01
£727.97 GBP
Quantity
Couldn't load pickup availability
Request quote or documents
![CDK2 degrader 1 [CAS 3036604-59-5]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
CDK2 degrader 1 (Compound 3) is a selective CDK2 molecular glue degrader with a Dmax (CDK2) of > 80% and a Ki (CRBN) > 1 μM. CDK2 degrader 1 binds to cereblon to induce ubiquitination and subsequent proteasomal degradation of the CDK2. CDK2 degrader 1 is used in the research of a wide range of cancers[1].
-
CAS Number
[3036604-59-5]
-
Molecular Formula
C23H27F2N3O4
-
Molecular Weight
447.47
-
Smiles
[H][C@](C1)(CC2)C[C@]2([H])[C@@H]1COC(NC3CN(C4=CC(F)=C(C5C(NC(CC5)=O)=O)C(F)=C4)C3)=O
-
Target
CDK; Molecular Glues
-
Isoform
CDK2
-
Purity
99.74
-
Solubility
DMSO : 100 mg/mL (ultrasonic)
-
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
-
Shipping Conditions
Room Temperature
Related Products
- QM-0054937 Tubulin polymerization-IN-74 [CAS 54491-43-9]
- QM-0016949-01 Tubulin polymerization-IN-75 [CAS 5325-66-6]
- QM-0015976 Tubulin-IN-62
- QM-0015963 Tubulin polymerization-IN-84 [CAS 2982893-14-9]
- QM-0015797 Tubulin-IN-61
- QM-0015796 Tubulin-IN-60
- QM-0015606 Tubulin-IN-59
- QM-0015240 Tubulin polymerization/P-gp-IN-1
- QM-0015176 Tubulin-IN-58
- QM-0015147 Tubulin-IN-57
Other industry favorites
- QM-0054937 Tubulin polymerization-IN-74 [CAS 54491-43-9]
- QM-0016949-01 Tubulin polymerization-IN-75 [CAS 5325-66-6]
- QM-0013259 Tubulin-IN-54
- QM-0013216 Tubulin-IN-53
- QM-0161799-01 VF 594 Click-iT EdU Universal Cell Proliferation Detection Kit
- QM-0161801-01 VF 488 Click-iT EdU Universal Cell Proliferation Detection Kit
- QM-0013784 Tubulin/LSD1-IN-1
- QM-0013695 Tubulin polymerization-IN-80
- QM-0151970-01 Tubulin/JAK2-IN-1 [CAS 2933938-46-4]
- QM-0151842-01 Tubulin polymerization-IN-47 [CAS 2834087-62-4]
CDK2 degrader 1 [CAS 3036604-59-5]
CDK2 degrader 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.