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CDK2-IN-12 [CAS 2410402-88-7]
CDK2-IN-12 [CAS 2410402-88-7]
SKU:QM-0068916
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Product Details
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Description
CDK2-IN-12 (compound 10b) is a potent CDK2 inhibitor, with an IC50 of 11.6 μM. CDK2-IN-12 inhibits hCA (carbonic anhydrase) isoforms I, II, IX and XII, with KI values of 3534, 638.4, 44.3, and 48.8 nM. CDK2-IN-12 shows anticancer activity[1].
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CAS Number
[2410402-88-7]
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Molecular Formula
C20H17N9O2S
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Molecular Weight
447.47
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Smiles
O=S(C1=CC=C(/N=N/C2=C3N=C(C4=CC=C(C)C=C4)C(C#N)=C(N)N3N=C2N)C=C1)(N)=O
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Target
Carbonic Anhydrase; CDK
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Isoform
CA II; CA IX; CDK2; CDK9
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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CDK2-IN-12 [CAS 2410402-88-7]
CDK2-IN-12 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.