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CDK2-IN-45
CDK2-IN-45
SKU:QM-0011012
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Product Details
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Description
CDK2-IN-45 (Compound 8f) is a CDK2 inhibitor (IC50: 0.64 μM) . CDK2-IN-45 inhibits the proliferation of DU-145 and PC-3 cell lines with IC50 of 2.20 μM and 4.17 μM, respectively. CDK2-IN-45 induces G0/G1 cell cycle arrest and apoptosis. CDK2-IN-45 can be used in prostate cancer research[1].
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Molecular Formula
C25H16ClN5S
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Molecular Weight
453.95
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Smiles
ClC(C=C1)=CC=C1C2=CC=NC3=C(C(NC4=CC=CC=C4)=NN32)C5=NC6=C(S5)C=CC=C6
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Target
Apoptosis; CDK
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Isoform
CDK2
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Shipping Conditions
Room temperature
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CDK2-IN-45
CDK2-IN-45 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.