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CDK2-IN-47
CDK2-IN-47
SKU:QM-0014993
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Product Details
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Description
CDK2-IN-47 is a potent CDK2 inhibitor with an IC50 of 0.21 μM. CDK2-IN-47 exhibits outstanding anticancer activity against MCF-7, HCT-116, and MGC-803 cell lines. CDK2-IN-47 effectively induces G1 cell cycle arrest, retinoblastoma protein (Rb) dephosphorylation, and significant apoptosis. CDK2-IN-47 can be used for the studies of breast cancer, colorectal cancer and gastric cancer[1].
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Molecular Formula
C16H23N5O4S
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Molecular Weight
381.45
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Smiles
O=C1C(C)=CN(CC(N[C@H](CC(C)C)C(OC)=O)=O)C2=NC(SC)=NN12
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Target
Apoptosis; CDK
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Isoform
CDK1; CDK2; CDK4; CDK6; CDK7; CDK9
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Shipping Conditions
Room temperature
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CDK2-IN-47
CDK2-IN-47 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.