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CDK2-IN-49
CDK2-IN-49
SKU:QM-0015798
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Product Details
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Description
CDK2-IN-49 (Compound 5j) is a CDK2 inhibitor with an IC50 of 0.25 μM. CDK2-IN-49 shows potent activity against CDK7 with an IC50 of 0.14 μM. CDK2-IN-49 induces Apoptosis by raising the levels of p53 and Bax protein expression while reducing the amount of Bcl-2. CDK2-IN-49 inhibits cell division. CDK2-IN-49 can be used in the research of cancer[1].
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Molecular Formula
C20H18N6O
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Molecular Weight
358.4
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Smiles
COC1=CC=C(C=C1)/N=N/C2=C3N=CC=C(N3N=C2N)C4=CC=C(C=C4)C
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Target
Apoptosis; Bcl-2 Family; CDK; MDM-2/p53
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Shipping Conditions
Room temperature
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CDK2-IN-49
CDK2-IN-49 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.