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CDK4/6/BRD4-IN-1
CDK4/6/BRD4-IN-1
SKU:QM-0011335
Price on request
Quantity
Request quote or documents
Product Details
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Description
CDK4/6/BRD4-IN-1 (B15) is an inhibitor of CDK4, CDK6 and BRD4, with IC50 values of 220 nM, 146 nM, 106 nM and 85 nM for BRD4-BD2, BRD4-BD1, CDK6 and CDK4, respectively. CDK4/6/BRD4-IN-1 (B15) can be used in the study of NSCLC (Non-Small Cell Lung Cancer) . CDK4/6/BRD4-IN-1 (B15) induces cell cycle arrest and apoptosis[1].
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Molecular Formula
C41H43FN10O6
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Molecular Weight
790.84
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Smiles
O=C(C1=CC2=CN=C(NC3=NC=C(N4CCN(C(COC5=C(OC)C=C(C(N6)=NC7=C(C=C(F)C=C7)C6=O)C=C5OC)=O)CC4)C=C3)N=C2N1C8CCCC8)N(C)C
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Target
CDK; Epigenetic Reader Domain
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Isoform
BD1; BD2; CDK4; CDK6
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Shipping Conditions
Room temperature
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CDK4/6/BRD4-IN-1
CDK4/6/BRD4-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.