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CDK4/6-IN-14 [CAS 2699091-15-9]

CDK4/6-IN-14 [CAS 2699091-15-9]

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SKU:QM-0069704

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  • Description

    CDK4/6-IN-14 is a potent and highly selective CDK4 and CDK6 (CDK) inhibitor with IC50s of 10 nM and 16 nM, respectively. CDK4/6-IN-14 exhibits more than 60-fold selectivity over CDKs 1, 2, 7, and 9, and shows high selectivity among other 205 kinases[1].

  • CAS Number

    [2699091-15-9]

  • Molecular Formula

    C24H27ClFN7O

  • Molecular Weight

    483.97

  • Smiles

    O=C1N(CC)CCC2=C1C=CC(C3=NC(NC4=NC=C(N5CCNCC5)C=C4)=NC=C3F)=C2.Cl

  • Target

    CDK

  • Isoform

    CDK1; CDK2; CDK4; CDK6; CDK7; CDK9

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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CDK4/6-IN-14 [CAS 2699091-15-9]

CDK4/6-IN-14 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.