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CDK4-IN-3 [CAS 3002399-75-6]

CDK4-IN-3 [CAS 3002399-75-6]

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SKU:QM-0008081-01

£797.23 GBP
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  • Description

    CDK4-IN-3 (Compound 389) is a potent irreversible cyclin-dependent kinase 4 (CDK4) inhibitor (IC50=25 nM, >10-fold selective over CDK6) . CDK4-IN-3 arrests the cell cycle at G₁ phase, and induces tumor cell apoptosis. CDK4-IN-3 is promising for research of solid tumors such as breast and lung cancers[1].

  • CAS Number

    [3002399-75-6]

  • Molecular Formula

    C26H32FN5O3

  • Molecular Weight

    481.56

  • Smiles

    CC(N1C2=CC(C3=NC(N[C@H]4[C@@H](COCC4)O)=NC=C3F)=CC=C2C(C(C)=C1C5CCCN5)=O)C

  • Target

    Apoptosis; CDK

  • Isoform

    CDK4; CDK6

  • Purity

    98.07

  • Solubility

    DMSO : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

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Variant Variant total Quantity Price Variant total
5 mgQM-0008081-01
5 mgQM-0008081-01
£797.23/ea
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£797.23/ea £0.00
10 mgQM-0008081-02
10 mgQM-0008081-02
£1,241.91/ea
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£1,241.91/ea £0.00
25 mgQM-0008081-03
25 mgQM-0008081-03
£2,435.05/ea
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£2,435.05/ea £0.00
50 mgQM-0008081-04
50 mgQM-0008081-04
£3,866.32/ea
£0.00
£3,866.32/ea £0.00
100 mgQM-0008081-05
100 mgQM-0008081-05
£6,150.52/ea
£0.00
£6,150.52/ea £0.00

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CDK4-IN-3 [CAS 3002399-75-6]

CDK4-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.