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CDK5-IN-4 [CAS 1212711-91-5]
CDK5-IN-4 [CAS 1212711-91-5]
SKU:QM-0084089
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Product Details
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Description
CDK5-IN-4 (compound 4) is a potent multikinase type-II inhibitor targeting CDK5, with an IC50 of 9.8 μM. CDK5-IN-4 also inhibits GSK-3α, GSK-3β, CDK9, and CDK2, with IC50 values of 0.98, 4.00, 1.76, and 6.24 μM, respectively. CDK5-IN-4 can be used for glioblastoma research[1].
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CAS Number
[1212711-91-5]
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Molecular Formula
C24H24FN5O3
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Molecular Weight
449.48
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Smiles
O=C(N[C@H]1CO[C@@H]2[C@H](CO[C@H]12)NC3=NC(C4=CC=CC(F)=C4)=CC=N3)NCC5=CC=CC=C5
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Target
CDK; GSK-3
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Isoform
CDK2; CDK5; CDK9; GSK-3α; GSK-3β
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Shipping Conditions
Room temperature
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CDK5-IN-4 [CAS 1212711-91-5]
CDK5-IN-4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.