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CDK7/9-IN-1 [CAS 2747919-19-1]
CDK7/9-IN-1 [CAS 2747919-19-1]
SKU:QM-0066235
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Product Details
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Description
CDK7/9-IN-1 is a cyclin-dependent kinases 7/9 (CDK7/9) inhibitor. CDK7/9-IN-1 selectively inhibits CDK7 over CDK9. CDK7/9-IN-1 inhibits CDK7 with IC50s of 0.0656 μM and 0.00574 μM without pre-incubation and after 3 hours pre-incubation, respectively. CDK7/9-IN-1 inhibits CDK9 with an IC50 of 2.14 μM after 3 hours pre-incubation. CDK7/9-IN-1 can be used for the research of cancer[1].
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CAS Number
[2747919-19-1]
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Molecular Formula
C24H32F3N5O2
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Molecular Weight
479.54
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Smiles
CC(C1=CN=C2N1C=C(C(F)(F)F)C=C2NC3CCN(CC3)C[C@@H]4CN(CCO4)C(C=C)=O)C
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Target
CDK
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Isoform
CDK7; CDK9
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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CDK7/9-IN-1 [CAS 2747919-19-1]
CDK7/9-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.